What is wrong with your head?

Depigmentation of the substantia nigra and locus ceruleus = Parkinson's

Lewy bodies

Diffuse cortical atrophy with relative sparing of primary motor and sensory areas = Alzheimer's

Beta Amyloid plaques, neurofibullary tangles

Selective frontal and temporal lobe atrophy, gliosis, neuronal loss, swollen neurons = Pick Disease

Pick Bodies (silver staining cytoplasmic inclusions)

Striking degeneration of the caudate nucleus = Huntington's (autosomal Dominant)

Widespread neuronal loss and gliosis in subcortical areas = Supranuclear Palsy

Rabies = Negri bodies