Osteolytic = breaks bone down so osteoclasts are involved and enzymes like IL-1 and PGE2 are involved and stimulate the osteoclasts. Patient often has hypecalcemia.
Osteoblastic = builds bone so like the name suggests, osteoblasts are involved. The Alkaline Phosphatase would be elevated.
Lung = lytic
Prostate = Blastic
Breast = Both lytic and blastic
Multiple Myeloma = Lytic (cookie cutter lesions)
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